Of course we do!
I'll do my best explaining. If it's not clear let me know.
We teach our players something called cloudy and clear. Cloudy- can't see because the runner is between you and the target/thrower. Clear-both player move to the same side of the runner for a clear throwing lane. I'm sure everyone teaches this, but I have found naming it helps trigger the action. At a recent high school game I heard my former 10U catcher yell to my 10U first base person after a DTS, "You need to move to clear when the ball pulls me into foul ground."
The reason Pickles work for the runner is because they are allowed to jockey back and forth creating many throws and possible obstruction calls. The key is to make them sprint. Once they sprint the defense gains an advantage, because it becomes much harder to change direction.
To be successful you must believe you are going to get the out. If you believe you can execute the one throw run down then you have to be willing to break from the age old "always run her back to the previous base-never chase her to the next base." Running her back to the previous base only matters if you plan for the runner to be safe. I'm planning for her to be out. I don't care if she's out running toward second base or third base- just get her out.
How to:
So a runner gets caught between bases. Lets use 3rd and home for the explanation. Who ever has the ball must sprint at her we will pretend it's 3B. You want to tag her out. You must stress that. The tag out makes a zero throw run down. When the fielder sprints the runner sprints. The runner now has her back to the ball and is in the dark. C and 3b must make sure that they have moved to clear. If 3b can not tag the runner they make the easy throw to C for the tag out. The timing of the throw is essential. If the throw is too early you'll create a pickle, but due to the fact that the runner is on a dead sprint and can't see when the throw is made your catcher should be able to run and tag her. If timed right the catcher will have an easy tag out.
The keys:
Both fielders be in clear.
Make the runner sprint.
Don't make the throw too early. It must be late enough for the tag, or the receiving fielder to catch the runner as she slams on the breaks to switch directions.