2B is not SS..have there been any All-American lefty SS? Again, SS have the least amount of time to get the ball to 1st base of all the IF. My freshmen year in college I switched from SS, which I had played all my life, to 2B. The difference in what I am speaking about regarding getting the ball out quickly was quite eye-opening.
Lefty 2b I can see working at a high level since while disadvantaged in throwing to first, which is less important at 2B than SS since you have more time to get the ball to 1st, they have an advantage over RH when throwing to 2B on DP. As a RH 2B that was the most difficult thing for me to learn to do correctly and efficiently.
At the NAIA level yes. Amy Nanson in 2006. She was a 3 time All American at 3 different positions LF, 1B, and SS. I am not trying to say it is the ideal spot. I am only saying the right player can make it work.